Anti-Adrenergic Effects of Nitroglycerin on the Heart
نویسنده
چکیده
The therapeutic effect of nitroglycerin is geneially attributed to its coronary dilator effect alone. In contrast, it could be shown that nitroglycerin also counteracts the chronotropic as wvell as the electiocardiographic T-wave (leplessing effects of epinep)hline, arterenol and caldiac syml)athinl upon the heart. Accordingly, its therapeutic action in angina pectoris is suspected as being largely due to a chemical protection of the heart muscle against the chemically anoxialpro(lucing effects of sympathoniimetic amines.
منابع مشابه
Studies of the Antiadrenergic Effects of Nitroglycerin on the Dog Heart By RICHARD
were studied. Observations were made upon changes in heart rate, myocardial oxygen consumption, systolic vigor, and the electrocardiograms. Data are presented showing the effects of nitroglycerin and adrenergic agents when given separately and in combination. Results indicate that in dogs, nitroglycerin produces no antiadrenergic effects on the myocardium. The suggestion is made that the T wtav...
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تاریخ انتشار 2005